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NADPH, which is critical for GSH conversion in the mitochondrial TCA cycle, is catalyzed by NADP+-dependent isocitrate dehydrogenase (IDH), and its cytoplasmic source can be provided by the reversible oxidative decarboxylation of malate to pyruvate catalyzed by malic enzyme 1 (ME1)

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Understanding Acid Reflux Acid reflux, or gastroesophageal reflux disease (GERD) when it becomes chronic, occurs when the lower esophageal sphincter (LES) does not close properly

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The area postrema, the brainstem region most responsible for drug-induced nausea, is packed with serotonin receptors